Tag:

cellular stress

An IGFBP receptor sows death form above: meet TMEM219, a face-off(ender) of gut staminality

An international study led by Dr. Paolo Fiorina from Boston Children's Hospital and in collaboration with researchers from University of Milan highlights the beneficial...

SAMTOR: the aminoacid naviGATOR making TORC to help cancer cells for their unMET requirements

The mTOR complex (mTORC1) regulates cell growth and metabolism in response to multiple environmental signals. Nutrients signal via Rag proteins (GTPases) to promote the...

No pain, no gain: not true for ion flows regulating cartilage loss in osteoarthritis

Osteoarthritis (OAS) is characterized by cartilage degeneration with the loss of the extracellular matrix that allows the joint to compress without damage. The chondrocytes...

Glutathione: the natural cellular defensor regulated by the diet

Introduction Glutathione (GSH) is a low molecular weight, antioxidant and the most abundant non-protein thiol in mammals, which plays an important role in peroxide detoxification,...

ALS: cellular stressors and basic activity wake up the sick gene

Patients with amyotrophic lateral sclerosis (ALS) frequently have a string of repeated DNA code in brain neurons, carrying hundreds to thousands of copies within...