Tag:
mitochondria
ENGLISH MAGAZINE
Autoimmunity crosses alteRNAtive threads: meet SLIRP and its mitochondrial businesses
SLIRP: an anomalous factotum on nuclear signaling
SLIRP (SRA stem-loop interacting RNA binding protein) was firstly identified in 2006 and found to bind to a...
ENGLISH MAGAZINE
“Bloody” aging stems from methylome: and DNMT 3s the energy out of the mitochondria
As we age blood stem cells, the essential source of new blood cells in the body, can accumulate genetic mutations. These mutations can give...
ENGLISH MAGAZINE
Aminoacids and fats meet for “malignant” purposes: reexploring antipsychotic drugs paving the way for metabolic wreck
Glioblastoma (GBM) is the most lethal brain tumor, with a median survival rate of merely 12-16 months after diagnosis. Despite surgical, radiation and chemotherapy...
ENGLISH MAGAZINE
DNA is where pluripotency STEMS: but mitochondria “renew it all” with their protein networks “edging” to death
Mitophagy is a selective form of macro-autophagy in which unwanted or damaged mitochondria are preferentially targeted for degradation at the auto-phago-lysosome, as an adaptative...
ENGLISH MAGAZINE
Cancer kills by lactate: how cellular junk becomes a signal to acquire more fuel and waste the body to death
Cachexia is a complex metabolic syndrome associated with rapid loss of body weight, mainly loss of fat and lean muscle. Patients with cancer cachexia...
ENGLISH MAGAZINE
Antioxidants: not all of them match for mitochondrial needs
Mitochondria are tiny structures in human and animal cells that produce energy through an integrated series of chemical reactions known as the respiratory chain...
ENGLISH MAGAZINE
NAD+: does the hidden metabolism mirrors to tissue health?
Nicotinamide adenine dinucleotide (NAD+) is called the "anti-aging molecule" because research has shown that its levels fall with age and that restoring them can...
ENGLISH MAGAZINE
Cancer stem cells: an “old glory” works unexpectedly great against
Cancer stem cells (CSCs), also known as cancer-causing cells, are a hot topic among researchers. These cells are resistant to current treatments and play...
