English Magazine

Genetic ataxia on the move: beyond molecules, the “no pain no gain” formula seems to delay the onset

Friedreich’s ataxia (FRDA) is the most common autosomal recessive ataxia in the Caucasian population with detrimental clinical symptoms, including ataxia, muscle weakness, type 2 diabetes and heart failure. These symptoms usually first appear in childhood or […]

Diabete: capire di più i grassi permette di trovare strategie nuove
English Magazine

Muscle strenght and renewal: relying on mitochondria and how exercise boost them all

Because of the role of the mitochondria in metabolic and overall health, previous research has suggested that dysfunction in these organelles may have implications in conditions such as obesity and diabetes. Other conditions that mitochondrial dysfunction is […]

English Magazine

Parkinson disease: the old hidden polyamine transport mystery finally unveiled

Aging is the major risk factor for many chronic disorders, including diabetes mellitus, cancer, cardiovascular diseases, and neurodegenerative diseases including Parkinson disease (PD), whose current treatment is limited to symptomatic relief. Because PD prevalence increases with […]

English Magazine

Friedreich ataxia: from the mechanisms to a cure, the limit is the knowledge

Friedreich’s ataxia is a genetic a neurodegenerative disease that leaves its victims with difficulty walking, a loss of sensation in the arms and legs and impaired speech caused by degeneration of nerve tissue in the […]

English Magazine

Liver cancer: a couple of old glories seem to bring SALLvation at hand

Liver cancer is the sixth most common cancer worldwide, affecting about 24 individuals in every 100,000 people a year. Hence, the current lack of therapeutic options for it is a grave concern. Hepatocellular carcinoma (HCC) […]

English Magazine

Genetic ataxia: SCAvenging the mutation is far, better to SirTwining with “energy”

Spinocerebellar ataxia type 7 (SCA7) is an inherited neurodegenerative disorder that causes progressive problems with vision, movement, and balance. Individuals with SCA7 have CAG-polyglutamine repeat expansions in one of their genes; these expansions lead to […]