Tag:
transcription factor
ENGLISH MAGAZINE
“Oh My oD, are you both enhancer and silencer? Where do your muscles stem from?”
For more than 30 years, scientists have studied how the myogenic determination gene number 1 (MyoD) protein binds DNA to modify the gene expression...
ENGLISH MAGAZINE
Neur-on-aging recovered: GTP closes ATP into the cellular redox workouts
Age is the largest risk factor for Alzheimer’s disease (ALD), but the age-related mechanisms that increase risk for ALD are unclear. Although a proposed...
ENGLISH MAGAZINE
Prostate cancer PROSPERity is out of the BOX: and metastasis “stems” from core HD ACes
Researchers at the University of Michigan Rogel Cancer Center identified a gene that plays a key role in prostate cancer cells that have transitioned...
ENGLISH MAGAZINE
RanBP2 in cancers: a SUMO fighter on the “surface” to be defeated in the “core”
The nuclear pore complex protein RANBP2 has emerged as a critical factor in the development and progression of various solid malignancies. As a SUMO...
ENGLISH MAGAZINE
FOXes R 2 clever to go undetected: but when it comes to children, “targeted” shots are needed
Pediatric tumors are a field of oncology that has always had special attention that needs no explanation. Tumors such as neuroblastoma and medulloblastoma are...
RICERCA & SALUTE
Il fattore LXR-beta: un recettore nucleare che dal metabolismo passa al controllo di ansia e depressione
Cos'è LXRβ?
LXRβ, che appartiene alla famiglia dei recettori nucleari dei fattori di trascrizione attivati ​​da ligando, controlla il metabolismo del colesterolo e l'infiammazione. Diversi...
ENGLISH MAGAZINE
AP-1: a keymaster FOStering the JUNction among several tissues by wERKing on the cellular MAPk
AP-1: ID and biological functions
AP-1 (Activator Protein-1) is a transcription factor that plays a key role in regulating gene expression involved in a wide...
ENGLISH MAGAZINE
Aminoacids and fats meet for “malignant” purposes: reexploring antipsychotic drugs paving the way for metabolic wreck
Glioblastoma (GBM) is the most lethal brain tumor, with a median survival rate of merely 12-16 months after diagnosis. Despite surgical, radiation and chemotherapy...
