Tag:

bone marrow

“Bloody” aging stems from methylome: and DNMT 3s the energy out of the mitochondria

As we age blood stem cells, the essential source of new blood cells in the body, can accumulate genetic mutations. These mutations can give...

Iron eating “stems off”: how to solve an AMLetic doubt to kill dormant leukemic progenitors

Acute myeloid leukemia (AML) is the most common cancer of the blood and bone marrow in adults. Caused by an increase in immature cells...

Marrow stem cells enterprising toward aging: a journey among receptors, cytokines, signaling, “fatty” stores and lifestyle

The aging immune system is associated with reduced lymphopoiesis, increased inflammation, and bone marrow diseases due to alterations in self-renewing haematopoietic stem cells (HSCs)....

Heart MIRs in outer space: the answer stems from the marrow

University of Alabama at Birmingham researchers now report that exosomes are key to the SOS signal that the heart muscle sends out after a...

Myelofibrosis: vitamin D does not help the marrow at all

There are three types of blood cell: white blood cells, red blood cells  and platelets. All three types are created from hematopoietic stem cells...

CDK6: once removed, the mutant gets JAcK 2 order

Myeloproliferative neoplasms (MPNs) are a group of rare, malignant diseases of the bone marrow involving the production of an excess of red blood cells,...

Needed therapy. STAT. Transcription selectivity in 5 minutes

An international research team led by researchers from Vetmeduni Vienna have made an important discovery that could lead to a better understanding of lymphocytic...

Myelofibrosis: combination is far better than a single agent

Myelofibrosis is a severe and very rare hematological disease for which treatment has only been partially effective to date. It is a Philadelphia chromosome-negative...