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MCL-1 to the rescue: BH domains set 3 breast cancer from death

A protein frequently found in high levels in breast cancer cells helps tumors to survive and grow, and could be targeted with a new...

Dementia and diabetes: cholesterol itself finds a way to escApoE

There is no known cure for Alzheimer's disease, which affects more than 5.5 million people in the United States. In the last decade, scientists...

Big Apple variant official: is there gonna be concern for another viral “spike”?

New research led by Patrick McGann from Walter Reed Army Institute of Research found the first cases of the B.1.1.220 variant with an E484K...

Estrogen receptors, signaling and targeting: in the midst of molecules to beat breast cancer

Estrogen receptors: how do they work? The estrogen receptor exists in two forms, ERα and ERβ, that are transcribed from unique genes and have different...

Against southafrican variant: mRNA vax get overcome by ciRNA technology

The speed of development of the COVID-19 vaccine is unprecedented, with six of them already approved for emergency use. One of the most pervasive...

Targeting heart failure: looking beneath receptors, possibilities may become G-gantic

Chronic heart failure is a complex chain of events that lead the heart to loose its ability to pump blood across all bodily blood...

COVID vaccine side effects: they are all on “nano-reasons”

Lipid nanoparticles (LNPs) are the carrier vehicles that protect messenger RNA (mRNA) molecules from degradation and aid intracellular delivery and endosomal escape in the...

Varian(t)bility spikes: either english and brasilian coronavirus jump faster than primeval

SARS-CoV-2 has a slower mutation rate compared to other RNA viruses. However, because of the coronavirus disease 2019 (COVID-19) pandemic and high transmissibility, the virus...

When all receptors look alike but they’re not: this is how pancreas copes to work tasks out

The insulin that is released by the beta cells of the pancreas is the main regulator of blood sugar. Previous and current studies by...

Nitrogen metabolism: the “in plain sight” target to uproot cancers’ “hidden pathways”?

Nitrogen is a building block of all proteins in the body, RNA and DNA, so tumors are greedy for this element. When the body...

“Houston we have a problem: COVID variants are on a collision course and approaching”

New research led by a team at Houston Methodist Hospital in the United States has modeled the aggressive genomic sequencing of severe acute respiratory...

Review “on the field” about vaccines efficacy in England: are there hopes for a “single shot”?

The current outbreak of coronavirus disease 2019 (COVID-19) has caused a dramatic loss of human life and devastated the healthcare systems and socioeconomic structures...

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