Tag:

cancer cells

Cance(r)ling resistance: how lactate can be exploited to boost immune defences in oncology

Lactic acid (LA) has transitioned from being perceived as a mere glycolytic waste product to a pivotal regulator of tumor-immune crosstalk. Historical milestones—from Scheele's...

Pro state of the art: ARresting cancer by GRabbing chromatin to ERase gene accessibility

Glucocorticoids are steroid hormones that are also used as drugs. Owing to their strong anti-inflammatory effect, synthetic glucocorticoids are among the most prescribed group...

Prostate cancer PROSPERity is out of the BOX: and metastasis “stems” from core HD ACes

Researchers at the University of Michigan Rogel Cancer Center identified a gene that plays a key role in prostate cancer cells that have transitioned...

Finding the Tau of leukemia: the TAUTological focusing on glucose metabolism was not foreseen

A new scientific study identified taurine, which is made naturally in the body and consumed through some foods, as a key regulator of myeloid...

FOXes R 2 clever to go undetected: but when it comes to children, “targeted” shots are needed

Pediatric tumors are a field of oncology that has always had special attention that needs no explanation. Tumors such as neuroblastoma and medulloblastoma are...

Melanoma drug resistance get overcome: without GSK3 cells are B-Raft of advantage

Melanoma is a type of skin cancer in which nearly half of patients have mutations in the BRAF gene that accelerate tumor growth. Although...

SAMTOR: the aminoacid naviGATOR making TORC to help cancer cells for their unMET requirements

The mTOR complex (mTORC1) regulates cell growth and metabolism in response to multiple environmental signals. Nutrients signal via Rag proteins (GTPases) to promote the...

Brain cancer “going APE”: here is its way to resist TMZ and leave DNA repair BEReft with options

In spite of intensive research, glioblastoma remains one of the most lethal types of brain cancer. Despite there are several available medications, temozolomide (TMZ) is...