Reactive oxidant species (ROS) accumulation is key to osteoclast differentiation, a phenomenon related to bone reabsorption and the onset of osteoporosis. Plant-derived polyphenols that…
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As we age blood stem cells, the essential source of new blood cells in the body, can accumulate genetic mutations. These mutations can give…
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Pediatric tumors are a field of oncology that has always had special attention that needs no explanation. Tumors such as neuroblastoma and medulloblastoma are…
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Opioid and endocannabinoid transmission is not just an “acute” signaling system related to pleasure, analgesia, or emotional regulation; it is, in fact, a modulatory…
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Stem cell proliferation and differentiation Stem cells have garnered significant attention in biomedical research due to their unique capacity for self-renewal and differentiation into…
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Mitophagy is a selective form of macro-autophagy in which unwanted or damaged mitochondria are preferentially targeted for degradation at the auto-phago-lysosome, as an adaptative…
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Come altri fattori come l’età, il sesso e la genetica, il fumo ha un impatto importante sulle risposte immunitarie. Questa è la scoperta recentemente…
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Telomeres are specialized structures at the ends of linear chromosomes that protect genome stability. At their level, particular forms of chromatin may be found.…
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A protein known to play a role in cancer may also be increasing fibrosis in scleroderma patients. Systemic sclerosis (Scleroderma, SSc) is a systemic…
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Understanding and mitigating the role of epigenetics (environmental influences that trigger changes in gene expression) in disease development is a major goal of researchers.…
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