Tag:

histone deacetylase

DNA is where pluripotency STEMS: but mitochondria “renew it all” with their protein networks “edging” to death

Mitophagy is a selective form of macro-autophagy in which unwanted or damaged mitochondria are preferentially targeted for degradation at the auto-phago-lysosome, as an adaptative...

Lactate: that useless disposable junk, working as a genetic regulator in cancer cells

Described by Otto Warburg a century ago, accelerated glucose consumption and lactate production under fully aerobic conditions is ubiquitous in solid cancers. Observations of...

Osteoporosis surfs epigenetics: is histone methylation relying on gender to take its effects?

Nearly 19% of american women aged 50 and older have osteoporosis in their hips and lower spines. Osteoporosis-associated weakening of the bones increases the...