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English Magazine

Myelofibrosis: vitamin D does not help the marrow at all

There are three types of blood cell: white blood cells, red blood cells  and platelets. All three types are created from hematopoietic stem cells located in the bone marrow. Myelofibrosis causes an abnormal increase in […]

Il nuovo farmaco ammazza-leucemia alle prove: venetoclax
English Magazine

CDK6: once removed, the mutant JAcK 2 order

Myeloproliferative neoplasms (MPNs) are a group of rare, malignant diseases of the bone marrow involving the production of an excess of red blood cells, white blood cells and/or platelets. MPNs are chronic diseases with only […]

English Magazine

Medulloblastoma: on the hunt for mutations and solutions

Among young children, medulloblastoma is among the most common form of brain tumor. Medulloblastoma, which is divided into four subgroups, is partially caused when a mutation occurs in the “driver genes” that either promote or […]

Nuovo gene per la SLA: studio internazionale vede partecipe anche l'Italia
English Magazine

ALS: cellular stressors and basic activity wake up the sick gene

Patients with amyotrophic lateral sclerosis (ALS) frequently have a string of repeated DNA code in brain neurons, carrying hundreds to thousands of copies within the gene C9orf72. New research looks at what triggers these repeated […]

Sarcomas:
English Magazine

Sarcomas: high throughput screening to lock the receptor

A new compound that targets a receptor within sarcoma cancer cells shrank tumors and hampered their ability to spread in mice and pigs, a study from researchers at the University of Illinois reports. The researchers […]

DNA shuffling
English Magazine
Tamoxifen: from breast cancer it switches to genetic muscle disease
English Magazine
Mutations: not just in overt cancer
English Magazine

Mutations: not just in overt cancer, the hotspot lights up earlier

  Mutations in healthy tissue are known as somatic mutations. As people age, mutations in their DNA slowly build up.  Because cancer is the result of an accumulation of genetic mutations, understanding how these add up over […]

Sindrome CMT: quando il problema "tiene mani e piedi legati"
English Magazine

CMT syndrome: the mechanism beneath that keeps “tied hands and feet”

About 1 in 2,500 people have a degenerative nerve disease called Charcot-Marie-Tooth (CMT). The disease is typically diagnosed in children, who may lose their ability to walk and use their hands for fine motor skills. […]

Terapia genica: SLA e SMA saranno le prossime?
Ricerca & Salute

Gene therapy: would ALS and SMA be the next candidates?

Spinal muscular atrophy and amyotrophic lateral sclerosis are two devastating neurological conditions with the common pathological sign of motor neuron degeneration, which eventually leads to muscle wasting and death. While the etiology, age of onset, […]