Tag:

stem cells

AML fighting is not MENINgless: SRChing Akt-ting kinases and a nuclear-mine to kill the stem

Acute myeloid leukemia (AML) is the deadliest form of leukemia, with a median survival of less than nine months and a 5-year survival rate...

An IGFBP receptor sows death form above: meet TMEM219, a face-off(ender) of gut staminality

An international study led by Dr. Paolo Fiorina from Boston Children's Hospital and in collaboration with researchers from University of Milan highlights the beneficial...

“Bloody” aging stems from methylome: and DNMT 3s the energy out of the mitochondria

As we age blood stem cells, the essential source of new blood cells in the body, can accumulate genetic mutations. These mutations can give...

Bones to Enterprise: “Set the BLASTS toward the NKD Wing 4D hull strenght”

Osteoporosis, a condition that weakens bones and heightens the risk of fractures, poses a significant public health challenge, especially among postmenopausal women. The disease...

Expanding the roots or letting them committ: either way metabolism rules tissue “stamina” in good and bad fates

Stem cell proliferation and differentiation Stem cells have garnered significant attention in biomedical research due to their unique capacity for self-renewal and differentiation into various...

Iron eating “stems off”: how to solve an AMLetic doubt to kill dormant leukemic progenitors

Acute myeloid leukemia (AML) is the most common cancer of the blood and bone marrow in adults. Caused by an increase in immature cells...

Geraniol: the aromatic natural that would prevent senile dementia?

Although cardiovascular diseases, diabetes and cancers still have their high prevalence, life expectancy in the 21st century is increasing resulting in an increase in...

Marrow stem cells enterprising toward aging: a journey among receptors, cytokines, signaling, “fatty” stores and lifestyle

The aging immune system is associated with reduced lymphopoiesis, increased inflammation, and bone marrow diseases due to alterations in self-renewing haematopoietic stem cells (HSCs)....