Tag:

gene expression

Pro state of the art: ARresting cancer by GRabbing chromatin to ERase gene accessibility

Glucocorticoids are steroid hormones that are also used as drugs. Owing to their strong anti-inflammatory effect, synthetic glucocorticoids are among the most prescribed group...

A TRIP-to-lide on the MED side: another terpene and polyphenol combo for the autoimmune aREA

Rheumatoid arthritis (REA) is a progressive autoimmunity characterized by chronic inflammation and bone destruction, primarily driven by the overactivation of osteoclasts (OSCs). Current treatments often...

Prostate cancer PROSPERity is out of the BOX: and metastasis “stems” from core HD ACes

Researchers at the University of Michigan Rogel Cancer Center identified a gene that plays a key role in prostate cancer cells that have transitioned...

“Bloody” aging stems from methylome: and DNMT 3s the energy out of the mitochondria

As we age blood stem cells, the essential source of new blood cells in the body, can accumulate genetic mutations. These mutations can give...

Melanoma drug resistance get overcome: without GSK3 cells are B-Raft of advantage

Melanoma is a type of skin cancer in which nearly half of patients have mutations in the BRAF gene that accelerate tumor growth. Although...

Bach 2 the skintrack: a-topic to explore to treat dermatitis making easier MAREs to trot

Atopic dermatitis is an allergy that affects an average of about 5% of the general population, with symptoms closely related to social stress. In...

Opioid and endocannobinoid signaling: surface reach “the core” to regulate our mood

Opioid and endocannabinoid transmission is not just an “acute” signaling system related to pleasure, analgesia, or emotional regulation; it is, in fact, a modulatory...

Tetracyclins: old antibiotics committable for human diseases?

Background Tetracyclines are an old class of antibiotics that have been used for specific infections such as brucellosis, Lyme disease, rickettsiosis (e.g. Rocky Mountain spotted...