Tag:

protein kinase

AML fighting is not MENINgless: SRChing Akt-ting kinases and a nuclear-mine to kill the stem

Acute myeloid leukemia (AML) is the deadliest form of leukemia, with a median survival of less than nine months and a 5-year survival rate...

Complement-aRy roles for immune proteins in skin cancer: C5 triggers metastasis with α “q” of signals

Cutaneous squamous cell carcinoma (cSCC), a type of skin cancer, it's the second most common type of skin cancer, after basal cell carcinoma and...

The host and the guest challenge each other: chemistry games help the one doing the job of the other

Reactive oxidant species (ROS) accumulation is key to osteoclast differentiation, a phenomenon related to bone reabsorption and the onset of osteoporosis. Plant-derived polyphenols that...

An IGFBP receptor sows death form above: meet TMEM219, a face-off(ender) of gut staminality

An international study led by Dr. Paolo Fiorina from Boston Children's Hospital and in collaboration with researchers from University of Milan highlights the beneficial...

Personalized medicine in type 2 diabetes: the influence of phospho-proteome and gender

Type 2 diabetes (T2D) is a rapidly growing metabolic condition worldwide characterized by increased blood glucose levels during fasting or after food consumption. T2D...

Bone strenghts funNELL 2 genetic: kinases may be no the only FAKtotum in cellular AKTs

Osteoporosis, a widespread bone disease affecting millions globally, is caused by an imbalance between bone resorption and formation. Current treatments primarily inhibit bone resorption,...

Melanoma drug resistance get overcome: without GSK3 cells are B-Raft of advantage

Melanoma is a type of skin cancer in which nearly half of patients have mutations in the BRAF gene that accelerate tumor growth. Although...

Bach 2 the skintrack: a-topic to explore to treat dermatitis making easier MAREs to trot

Atopic dermatitis is an allergy that affects an average of about 5% of the general population, with symptoms closely related to social stress. In...