English Magazine

Myelofibrosis: vitamin D does not help the marrow at all

There are three types of blood cell: white blood cells, red blood cells  and platelets. All three types are created from hematopoietic stem cells located in the bone marrow. Myelofibrosis causes an abnormal increase in […]

Il nuovo farmaco ammazza-leucemia alle prove: venetoclax
English Magazine

CDK6: once removed, the mutant JAcK 2 order

Myeloproliferative neoplasms (MPNs) are a group of rare, malignant diseases of the bone marrow involving the production of an excess of red blood cells, white blood cells and/or platelets. MPNs are chronic diseases with only […]

English Magazine

Needed therapy. STAT. Transcription selectivity in 5 minutes

An international research team led by researchers from Vetmeduni Vienna have made an important discovery that could lead to a better understanding of lymphocytic leukemia. They identified the STAT5B protein as crucial for the development […]

Mielodisplasia: cosa è, come si complica e quali cure da fare
English Magazine

Myelofibrosis: combination is far better than a single agent

Myelofibrosis is a severe and very rare hematological disease for which treatment has only been partially effective to date. It is a Philadelphia chromosome-negative chronic myeloproliferative cancer clinically characterized by stem cell-derived clonal proliferation and […]

Multiple myeloma:
English Magazine

Multiple myeloma: a drug might become a stable maintenance ruler

Myeloma is a cancer of the plasma cells and it can affect several areas of the body, such as the spine, skull, pelvis and ribs. Current treatment usually involves chemotherapy and a stem-cell transplant. Hope […]

Leukemia: its
English Magazine

Leukemia stem cells: they are hungry for aminoacids rather than sugars

Most of animal cells rip apart sugar to release energy. Sometimes they rip apart fats, and in special circumstances, cells can even metabolize proteins. Cancer cells do things a little differently. First, most cancer cells […]

English Magazine

Graft versus host disease: a selective target already bears drugs in trial

Graft versus Host Disease (GVHD) is a potentially lethal side effect. that occurs when the donor’s immune cells attack the recipient’s normal tissues. Researchers at the Moffitt Cancer Center are trying to identify new drug […]

Alfa-fetoproteina: molto più di un marker da dosare
English Magazine

Alpha-fetoprotein: much more than a simple blood or cancer marker

Alpha-fetoprotein (AFP) is a well-known tumor marker and its production has been shown to correlate with the development of liver carcinoma, embryonal carcinoma, yolk sac tumors, teratocarcinoma, some testicular and ovarian tumors and hepatoblastoma. One […]

Un gene per l'anemia allunga la lista di quello per i tumori
English Magazine

The latest anemia gene enlenghtens the list for cancers actually

About genetic mutations are one of the main causes of cancer; they interrupt the normal processes that control cell growth, causing cell growth and the formation of tumors. Fortunately, only a small but significant percentage […]

Ossa e cartilagini e grasso: una proteina che li regola in comune
English Magazine

Bones, cartilages and fat: a common protein rules them all

Osteoporosis is a disease in which the bones become weak and brittle, increasing the risk of fracture. Bone is a living tissue that constantly regenerates and the body maintains a balance between the creation of […]