Tag:

signaling pathway

PROX1 and the indipendence of prostate cancer from androgens

Researchers at the University of Michigan Rogel Cancer Center have identified a gene that plays a key role in prostate cancer cells that have...

L’Impero non vincerà la Resistenza: il lato oscuro si chiama lattato e si rivolta contro

L'acido lattico è passato dall'essere percepito come un semplice prodotto di scarto glicolitico a un regolatore fondamentale del dialogo tra tumore e sistema immunitario....

The signaling hub won’t PIPe down: p53 pipping inositides to drag them into the “core” Akts

Several types of signalosome have been uncovered in the past twenty years about intracellular signaling; and many more will be surely discovered in the...

Let’s take a tryp tamin’ the loss: an old newrochemical drives “your hairs to stand”

Hair follicles are known to constantly cycle through phases of accelerated growth (called ‘anagen’), regression (‘catagen’), and rest (‘telogen’). This cycle and the balance...

AML fighting is not MENINgless: SRChing Akt-ting kinases and a nuclear-mine to kill the stem

Acute myeloid leukemia (AML) is the deadliest form of leukemia, with a median survival of less than nine months and a 5-year survival rate...

Complement-aRy roles for immune proteins in skin cancer: C5 triggers metastasis with α “q” of signals

Cutaneous squamous cell carcinoma (cSCC), a type of skin cancer, it's the second most common type of skin cancer, after basal cell carcinoma and...

Personalized medicine in type 2 diabetes: the influence of phospho-proteome and gender

Type 2 diabetes (T2D) is a rapidly growing metabolic condition worldwide characterized by increased blood glucose levels during fasting or after food consumption. T2D...

Bone strenghts funNELL 2 genetic: kinases may be no the only FAKtotum in cellular AKTs

Osteoporosis, a widespread bone disease affecting millions globally, is caused by an imbalance between bone resorption and formation. Current treatments primarily inhibit bone resorption,...