English Magazine

T-box for obesity, cancer and arthritis: 3 refer to 1

The worldwide epidemic of obesity has reached record levels, and what was once a problem only of industrialized countries is now also affecting the developing world. Consequently, scientists are working with great commitment to identify […]

English Magazine

Medulloblastoma: on the hunt for mutations and solutions

Among young children, medulloblastoma is among the most common form of brain tumor. Medulloblastoma, which is divided into four subgroups, is partially caused when a mutation occurs in the “driver genes” that either promote or […]

English Magazine

Eosino-philia for cancer: the hidden ancient weapon rises up

Eosinophils are white blood cells that secrete powerfully destructive proteins.Major basic protein 1 and 2 (MBP-1, MBP-2), eosinophil-derived neurotoxin (EDN), and eosinophil peroxidase all are cytotoxic proteins. EPO EPO catalyzes the oxidation of halides (chlorine, […]

Lung cancer needs lactate to grow: protease is the gatekeeper
English Magazine

Lung cancer needs lactate to grow: protease is the gatekeeper

UT Southwestern researchers have found that an enzyme on the surface of some lung cancer cells helps feed the cancer, making it a tempting treatment target. The enzyme, transmembrane serine protease 11B (TMPRSS11B) is described […]

Occult blood: differences between prevention and necessity for therapy
English Magazine

Occult blood: differences between prevention and necessity for therapy

Faecal occult blood test (FOBT) screening has been shown to decrease the incidence and mortality from colorectal cancer. Screening for colorectal cancer (CRC) reduces CRC mortality; many countries have implemented population-based CRC screening programmes and […]

OGG1: as
English Magazine

OGG1: as genome “greasemonkey” and inflammatory “mailman”

A multidisciplinary team of researchers led from Karolinska Institutet in Sweden have developed an anti-inflammatory drug molecule with a new mechanism of action. By inhibiting a certain protein, the researchers were able to reduce the […]

Mutations: not just in overt cancer
English Magazine

Mutations: not just in overt cancer, the hotspot lights up earlier

  Mutations in healthy tissue are known as somatic mutations. As people age, mutations in their DNA slowly build up.  Because cancer is the result of an accumulation of genetic mutations, understanding how these add up over […]