In the complex human gut ecosystem, white blood cells called macrophages play opposing yet complementary roles: some fight harmful microorganisms by triggering inflammatory reactions,…
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Maresins, resolvins, protectins and lipoxins are members of a super-family of specialized pro-resolving mediators (SPMs) enzymatically derived from polyunsaturated fatty acids (PUFAs) that orchestrate…
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Rheumatoid arthritis (REA) is a progressive autoimmunity characterized by chronic inflammation and bone destruction, primarily driven by the overactivation of osteoclasts (OSCs). Current treatments often…
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Vitiligo is a common disease that approximately affects 0.5% of the population worldwide, and more than half of the patients develop the disease between…
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Biology of thyroid hormones and their effects on the appendages The thyroid hormones, thyroxine (T4) and triiodothyronine (T3), play a crucial role in maintaining…
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Background Tetracyclines are an old class of antibiotics that have been used for specific infections such as brucellosis, Lyme disease, rickettsiosis (e.g. Rocky Mountain…
Leggi →Arthritis can affect children and adolescents of all races and ethnicities. However, according to the current study estimates for 2017-2021, about 220,000 children and…
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COVID-19 has caused unprecedented morbidity and mortality across the globe. The immune protection conferred by SARS-CoV2 vaccines and prior COVID-19 history, coupled with developing…
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Understanding and mitigating the role of epigenetics (environmental influences that trigger changes in gene expression) in disease development is a major goal of researchers.…
Leggi →Gluten is a protein complex present in wheat, barley and most cereals. Although many people have no problem digesting this protein, many people have…
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